Summary
What is
hyperthyroidism?
Hyperthyroidism, or overactive
thyroid, happens when your thyroid gland
makes more thyroid hormones than your body needs.
Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and mood. If not treated, hyperthyroidism can cause serious problems with your heart, bones, muscles, menstrual cycle, and fertility. But there are treatments that can help.
What
causes hyperthyroidism?
Hyperthyroidism
has several causes. They include:
- Graves' disease, is an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause.
- Thyroid nodules, which are growths on your thyroid. They are usually benign (not cancer). But they may become overactive and make too much thyroid hormone. Thyroid nodules are more common in older adults.
- Thyroiditis is inflammation of the thyroid. It causes stored thyroid hormone to leak out of your thyroid gland.
- Too much iodine. Iodine is found in some medicines, cough syrups, seaweed, and seaweed-based supplements. Taking too much of them can cause your thyroid to make too much thyroid hormone.
- Too much thyroid medicine. This can happen if people who take thyroid hormone medicine for hypothyroidism (underactive thyroid) take too much of it.
Who
is at risk for hyperthyroidism?
You
are at higher risk for hyperthyroidism if you:
- Are a woman
- Are older than age 60
- Have been pregnant or had a baby within the past 6 months
- Have had thyroid surgery or a thyroid problem, such as goiter
- Have a family history of thyroid disease
- Have pernicious anemia, in which the body cannot make enough healthy red blood cells because it does not have enough vitamin B12
- Have type 1 diabetes or primary adrenal insufficiency, a hormonal disorder
- Get too much iodine, from eating large amounts of foods containing iodine or using iodine-containing medicines or supplements
What
are the symptoms of hyperthyroidism?
The
symptoms of hyperthyroidism can vary from person to person and may include:
- Nervousness or irritability
- Fatigue
- Muscle weakness
- Trouble tolerating heat
- Trouble sleeping
- Tremor, usually in your hands
- Rapid and irregular heartbeat
- Frequent bowel movements or diarrhea
- Weight loss
- Mood swings
Goiter is an enlarged thyroid that may
cause your neck to look swollen. Sometimes it can cause trouble with breathing
or swallowing.
Adults over age 60 may have
different symptoms than younger adults. For example, they may lose their
appetite or withdraw from other people. Sometimes this can be mistaken for depression or dementia.
What
other problems can hyperthyroidism cause?
If
hyperthyroidism isn't treated, it can cause some serious health problems,
including:
- An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems
- An eye disease called Graves' ophthalmopathy. It can cause double vision, light sensitivity, and eye pain. In rare cases, it can lead to vision loss.
- Thinning bones and osteoporosis
- Fertility problems in women
- Complications in pregnancy, such as premature birth, low birth weight, high blood pressure in pregnancy, and miscarriage
How
is hyperthyroidism diagnosed?
Your
healthcare provider may use many tools to make a diagnosis:
- A medical history, including asking
about symptoms
- A physical exam
- Thyroid tests, such as
- TSH, T3, T4, and thyroid antibody blood tests
- Imaging tests, such as a thyroid scan, ultrasound, or radioactive iodine uptake test. A radioactive iodine uptake test measures how much radioactive iodine your thyroid takes up from your blood after you swallow a small amount of it.
What
are the treatments for hyperthyroidism?
The
treatments for hyperthyroidism include medicines, radioiodine therapy, and
thyroid surgery:
- Medicines for hyperthyroidism include
- Antithyroid medicines, cause your thyroid to make less thyroid hormone. You probably need to take the medicines for 1 to 2 years. In some cases, you might need to take the medicines for several years. This is the simplest treatment, but it is often not a permanent cure.
- Beta-blocker medicines, can reduce symptoms such as tremors, rapid heartbeat, and nervousness. They work quickly and can help you feel better until other treatments take effect.
- Radioiodine therapy is
a common and effective treatment for hyperthyroidism. It involves taking
radioactive iodine by mouth as a capsule or liquid. This slowly destroys the
cells of the thyroid gland that produce thyroid hormone. It does not affect
other body tissues. Almost everyone who has radioactive iodine treatment later
develops hypothyroidism. This is because the thyroid hormone-producing cells
have been destroyed. However, hypothyroidism is easier to treat and causes fewer
long-term health problems than hyperthyroidism.
- Surgery to remove
part or most of the thyroid gland is done in rare cases. It might be an option
for people with large goiters or pregnant women who cannot take antithyroid
medicines. If you have all of your thyroid removed, you will need to take
thyroid medicines for the rest of your life. Some people who have part of their
thyroid removed also need to take medicines.
- If you have hyperthyroidism, it's important not to get too much iodine. Talk to your health care provider about which foods, supplements, and medicines you need to avoid.

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